Trying to emerge in a swarmed Democratic field, Ms Warren told a group in Queens, New York, that she was "tired of freeloading extremely rich people".
Her administrative arrangement would turn around some tech mergers and prevent organizations from contending without anyone else stages.
This would advance challenge and shield independent companies, she said.
Ms Warren pinpointed the Amazon securing of WholeFoods as one she would turn around, alongside Facebook's merger with WhatsApp and Instagram, and Google's with Waze.
What's more, she said she would end practices, for example, Amazon selling individually Amazon Marketplace stage.
She plot her recommendations in a post on the site Medium. The organizations have not yet remarked.
Tech goliaths and the focus on their expenses
Amazon had wanted to construct another central station near where Ms Warren talked however pulled back plans a month ago, accusing nearby pioneers.
One lady at the rally, who was unsure about who to vote in favor of, stated: "What I like is that she's proposing enormous thoughts."
Heard over the noise
Investigation by BBC North America columnist Anthony Zurcher
Elizabeth Warren was the principal real Democrat to declare a 2020 presidential offer. She's since been joined by five of individual representatives, a present senator, a previous senator and an ex-bureau secretary, among others. In spite of the fact that she left the entryway first, the pack has rapidly gotten up to speed.
She's attempted to emerge from the group by proposing a progression of enormous, nitty gritty dynamic arrangements, including a "riches charge" on multimillionaires, general childcare and - in her most recent move - utilizing the administration's enemy of imposing business model influence to separate huge tech organizations.
She'll get an opportunity to put forth her defense for it on Saturday before what could be a not really inviting group, here at the South by Southwest innovation gathering in Austin, Texas. Government officials once in a while advantage from taking awkward - and politically unsafe - remains before generally thoughtful gatherings of people as an approach to demonstrate a touch of spine.
There is as yet an exceptionally long street ahead for Ms Warren, and her rivals - a large number of whom will likewise be on the Austin organize this end of the week. The Massachusetts congressperson is doing her best to be heard over the commotion - yet so is every other person.
Who is Elizabeth Warren?
A Massachusetts congressperson, she has considerable experience with law and strategy the scholarly world and sits on the dynamic left of the Democratic Party.
She burst on to the national scene following the 2008 monetary breakdown, supporting the production of the Consumer Financial Protection Bureau - an administration office that would fill in as a Wall Street guard dog and open promoter.
In 2010, after congressional section of the Dodd-Frank money related change charge, she helped the Obama organization set it up.
After two years, Ms Warren rode that rush of thoughtfulness regarding a seat in the US Senate, and on New Year's Eve she turned into the principal major Democratic possibility to report that she was arranging a presidential offered.
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